endocrine

Cushing's disease (hyperadrenocorticism)

Answer

Cushing's disease management in dogs typically costs $1,500 to $3,500 per year, including trilostane medication, monitoring bloodwork, and quarterly ACTH stim tests. Initial workup with low-dose dexamethasone suppression test adds $400 to $900. Insurance covers Cushing's when not pre-existing; it is a chronic condition requiring lifelong treatment.

Signs to watch for

  • 01Increased thirst and urination.
  • 02Pot-bellied appearance and muscle wasting.
  • 03Hair loss along the trunk, thin skin.
  • 04Panting at rest, ravenous appetite.

Treatment options

  • 01Trilostane (Vetoryl) — first-line medication, given once or twice daily.
  • 02Mitotane (Lysodren) — older alternative, requires careful induction.
  • 03Surgical removal of adrenal tumor for confirmed adrenal-dependent cases.
  • 04Quarterly ACTH stimulation testing for dose monitoring.

Prognosis: manageable

Typical cost in the US

ScenarioUSD
Low end (conservative care)$1,500
Median$2,400
High end (specialty / advanced)$3,500

Industry-aggregated ranges MerckAKC

How insurance handles it

Chronic condition: monthly medication and quarterly monitoring continue for life. A plan with no per-condition limit and high annual cap is meaningful here.

Frequently asked

Pituitary-dependent Cushing's (about 85 percent of cases) is managed, not cured, with lifelong medication. Adrenal-dependent Cushing's (about 15 percent) can sometimes be cured by surgical removal of the adrenal tumor.